Acyline

Alternative Name: GnRH II Receptor Antagonists

Reference target/product: GnRH II Receptor

Active Status: Unknown

Project Phase: Targets and Early Development

Mode: Hormonal

Description: A gonadotropin-releasing hormone II analog, acyline, has been developed. It is proposed that the contraceptive action of GnRH AIIA is through down-regulation of the GnRH II receptor. Further work is required to understand the full complexity of the antagonists action.

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